Serzone (nefazodone hydrochloride)
Common misspellings of this drug's name:
- Sirzone
- Sarzone
Serzone is thought to treat depression by correcting an imbalance in the amounts of certain natural chemicals in the brain, such as serotonin and norepinephrine. It is frequently prescribed for patients with Major Depressive Disorder (MDD), bipolar disorder, and anxiety disorders such as post-traumatic stress disorder (PTSD).
Cases of life-threatening liver failure necessitating a liver transplant and/or death have been reported in patients treated with Serzone. In December 2001, the FDA added a "black box" warning to Serzone's prescribing information labeling for doctors. Black box warnings call attention to situations involving considerable risk that might require additional information or monitoring to prevent an adverse effect, and are considered the most stringent warning the FDA can administer.
In November 2003, following discussions with Health Canada, Bristol-Myers Squibb Canada decided to discontinue its sales in Canada due to studies linking Serzone to adverse liver affects, including liver failure. Patients experiencing any of the following signs of liver dysfunction should see their doctor immediately:
- Yellowing of the skin or the whites of the eyes (jaundice)
- Unusually dark urine
- Loss of appetite that lasts several days or longer
- Nausea
- Abdominal pain
If you think you or a loved one has suffered damages due to taking the anti-depressant drug Serzone, you deserve the counsel of an experienced personal injury law firm skilled in handling dangerous drug cases. Contact us today to discover your best course of action.
For the latest information on Serzone:
